News - 2020

Jul 20, 2020

New publication

Please check out the second paper of the lab, published in the Journal of Neurophysiology. The study, led by Dr. Amelie Reynaud, shows an interesting phenomenon: human subjects tend to sacrifice their decisions when the movement they have to produce to report these choices are demanding in terms of accuracy. Data also suggest that there is no one single invigoration signal coordinating decision and action durations, but instead independent, yet interacting, urgency and vigor signals.

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Feb 02, 2020

New publication

Please check out the latest paper published in the Journal of Neurophysiology describing an ICMS experiment performed in Montreal with Paul Cisek. We show that stimulation of monkey PMd and, to  lesser extend, M1 delays the commitment to an action choice:

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Jan 16, 2020

New publication

The first paper of the lab is out !!! Check it out !

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News - 2019

Oct 30, 2019

Material update

Setup of the monkey lab in progress. Animals' training phase on the task about to start !

Oct 22, 2019

Sep 24, 2019

Material update

The EyeLink 1000 Plus just arrived ! Installation and calibration in progress. The goal is to accurately monitor monkeys' eye position and pupil size during decision making and movement execution.

Sep 04, 2019

Material update

The monkey restraint chair just arrived ! Animals' habituation phase about to start !!! 

Aug 15, 2019

Material update

Thank you very much to Dr. Karen Reilly (CRNL-Impact) for letting me her IM and surface EMG recording system (Grass QP511) ! Great tool to accurately measure reaching movement onset and vigor.

Also, by looking at old material in the unit, I came across this beautiful Grass S88 2 channel stimulator!

Apr 28, 2019

UPCOMING TALK:

Very pleased to contribute to the upcoming workshop on Cognitive Control and Performance Monitoring - In memory of Laurence Questienne

 

 

 

I will be giving a talk entitled:

Neural correlates of action decisions in a cortico-basal ganglia network

June 14, 2019 - 17.50 pm

Oostduinkerke, Belgium

Please check the full program

Apr 05, 2019

Upcoming talk:

Selection and invigoration of behavior: a role for the cortico-basal ganglia network

Friday, April 05, 2019, 12pm

Laboratoire de Neurosciences Cognitives et Computationnelles

Inserm - Ecole Normale Supérieure

29, rue d’Ulm, 75005 Paris

Mar 28-29, 2019

Insightful 2-retreat for the new Auvergne-Rhône-Alpes Inserm researchers in the beautiful domain Les Pensieres, a property belonging to the Merieux family in Veyrier-du-Lac

Jan 22, 2019

I'm hiring ! Please take a look at the official advertisement and feel free to contact me with any questions !

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News - 2018

Nov 16, 2018

The setup for the human experiments is ready !

A few software-related issues to fix, the ethical protocol to submit and wait for approval and experiments will begin. Expected date: January 2019

Oct 25, 2018

Lab setup in progress:

The office is almost complete, including brand new desk and computers !

The monkey ephy room is here, only needs some cleaning and then we'll start setting equipment up.

At the same time I'm working on an experimental setup dedicated to human subjects. Objective: cross-species comparison and fine-tuning of task parameters for monkey experiments

September, 2018

Please check out this book  chapter in which Paul Cisek and I summarize our recent work on the role of the PMd/M1-BG circuit during decision between actions, propose a way to map neural circuits and decision types and finally speculate on the respective functions of cortex and BG during goal oriented behavior.

https://www.taylorfrancis.com/books/e/9780429885945/chapters/10.4324%2F9780429467875-5

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April 6 & 7, 2018

Great speakers and attendees, cool conversations and beautiful weather at the "Probabilities and Optimal Inference to Understand the Brain" workshop in Marseille.

Thanks to the organizers for putting together this great event !

https://opt-infer-brain.sciencesconf.org/

SÉMINAIRE:

Régulation du compromis vitesse-précision pendant la prise de décision et l’exécution motrice : théorie, comportement et bases neuronales

Jeudi, 18 Janvier, 2018 à 10:30

 

Université du Québec à Montréal

Salle PK-5115, Pavillon Président-Kennedy (PK)
201, avenue du Président-Kennedy, H2X 3Y7

News - 2017

Our latest paper shows that the BG output is weakly involved in action selection but strongly controls decision urgency and speed-accuracy trade-off adjustments 

 

 

 

 

Neuron, 95:1160-1170, 2017

Please also check out this preview by Dr. Emilio Salinas

and the Highlight published in Nature Reviews Neuroscience by Dr. Katherine Walley

A new paper about the neural correlates of local (trial-to-trial) speed-accuracy trade-off adjustments in PMd and M1 during dynamic decisions is published: 

 

Trial-to-trial adjustments of speed-accuracy tradeoffs in premotor and

primary motor cortex

David Thura, Guido Guberman and Paul Cisek

Journal of Neurophysiology, 117(2):665-683, 2017

News - 2016

46th annual meeting of the Society for Neuroscience

November 12-16   |   San Diego   |   USA

I will be presenting a poster entitled:
The basal ganglia control the urgency of a reach choice, but not the choice itself
Session Number: 720
Session title: Physiology of Basal Ganglia Systems
November 16, 2016 - 8:00 AM = 12:00 PM
Convention Center - Halls B-H
San Diego, USA
The 38th International Symposium of the Groupe de recherche sur le système nerveux central (GRSNC)
 
 
The neuroscience of decision-making
 
 
May 2-3 2016, University of Montreal, Montreal, Canada

Our new paper about the neural correlates of speed-accuracy trade-off adjustments in PMd and M1 during dynamic decisions is published. 

 

Modulation of Premotor and Primary Motor Cortical Activity during Volitional Adjustments of Speed-Accuracy Trade-Offs

David Thura and Paul Cisek

 

Journal of Neuroscience, 20;36(3):938-56, 2016

News - 2015

Please see my opinion paper about models of decision-making :

 

How to discriminate conclusively among different models of decision-making

David Thura

 

Journal of Neurophysiology

DOI: 10.1152/jn.00911.2015

SfN annual meeting - Chicago - October 17-21, 2015

 

I'll be giving a nanosymposium talk entitled:

 

Evidence that the globus pallidus provides an urgency signal for decision-making

 

Session Time: October 20, 2015

1:00 pm - 5:00 pm

New paper :

 

The urgency-gating model can explain the effects of early evidence

Matthew A. Carland, David Thura and Paul Cisek

 

Psychonomic Bulletin & Review

DOI: 10.3758/s13423-015-0851-2

Invited talk:

 

Embodied decision-making during interactive behavior in a dynamic world

 

June 18, 2015  

 

Centre de Neuroscience Cognitive

UMR 5229 - CNRS et Université Claude Bernard Lyon I

Bron - FRANCE

Invited talk:

 

 

Embodied decision-making during interactive behavior in a dynamic world

 

February 4, 2015 | 3 - 4:30 p.m. | 5101 Tolman Hall 

 

UC Berkeley, Department of Psychology 

Berkeley (CA), USA

News - 2014

New paper published in the Journal of Neuroscience
December 03
 

 

Context-Dependent Urgency Influences Speed–Accuracy Trade-Offs in Decision-Making and Movement Execution

 

David Thura, Ignasi Cos, Jessica Trung, and Paul Cisek

 

Volume 34, Issue 49, 16442 - 16454, December 03, 2014

Translational and Computational Motor Control (TCMC) 2014

 

Friday November 14, 2014, Afternoon session

Renaissance Washington DC hotel, Renaissance Ballroom, East Salon

 

 

The neural dynamics of dynamic decisions

 

Jean-Francois Cabana, David Thura, Paul Cisek*

* Speaker

Séminaires étudiants de recherche du GRSNC 

 

Dynamic decisions about actions: Neural correlates of the

urgency-gating model

 

Tuesday October 21, 2014, 4.00 pm

Invited talk:

Dynamic decisions about actions:

 

Evidence for an embodied, urgency-based mechanism for reward rate maximization

 

Wednesday June 11, 2014, 1.30pm

Institut de Neurosciences des Systemes, Marseille (FRANCE)

Canadian Association for Neuroscience Meeting

 

May 25 - 28, 2014 - MONTREAL (Quebec), CANADA

 

 

Satellite: Linking primate brain circuits to behavior: advancements and applications

Sunday May 25, 9AM to 4:45PM

TalkMicro-stimulation of premotor and motor cortex affects choice duration during dynamic decision-making

 

D. THURA, P. CISEK

NEW PAPER PUBLISHED IN NEURON 

Deliberation and Commitment in the Premotor and Primary Motor Cortex during Dynamic Decision Making

David Thura and Paul Cisek

Neuron, Volume 81, Issue 6, 1401 - 1416, 19 March 2014

 

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