Internship positions are regularly available in my lab to study the neural activity in the cortico-basal ganglia circuits during foraging behavior in monkeys. If you're interested, feel free to contact me.
- D. -
16 avenue Doyen Lépine
69676 Bron Cedex
Phone: +33 (0)4 72 91 34 14
E-mail : firstname.lastname@example.org
Decision-making between actions
NEWS (last update: Oct 2023)
I was delighted to participate in a fantastic meeting organized by the GDR NeuralNet in the beautiful Marseille. I was able to present our recent data showing the coordination of decision and action in the cortex-basal ganglia network during foraging in macaques.
Very happy to have (modestly) contributed to this neuropharmacology study where we compare the effects of atomoxetine (noradrenaline antagonist) and reward on the behavior (motivation, perception, decision, action) of the macaque monkey . Congratulations to the whole team !
Very happy to have organized a symposium on decision-action interactions during goal-directed behavior on the occasion of NeuroFrance2023. Thanks to the talented speakers for agreeing to contribute:
Clara Saleri, Thomas Morvan, Nicolas Meirhaeghe, Gerard Derosiere and Thomas Michelet.
Happy to see this paper out in the European Journal of Neuroscience! We describe how humans adjust their decision and action in an integrated manner following decision and action errors.
Glad to share a new study in which we investigate the interplay between decision and movement efforts in healthy humans.
Happy to see this paper out in Plos Biology! With Jean-Francois Cabana, Albert Feghaly, and Paul Cisek.
October marks a major milestone for the laboratory and its development: our first multi-electrode recordings in the cortex and soon in the cortex-basal ganglia network of the behaving monkey.
Great news for the lab: the project BASALCOST, coordinated by David Robbe (Inmed, Marseille), with Bastien Berret (Université Paris-Saclay), is selected and funded by the @AgenceRecherche !
Goals: Reveling the behavioral determinants of foraging in various motor cost contexts and better understanding the role of the basal ganglia in this behavior.
New published review
I am glad to promote a new review published in the Oxford Research Encyclopedia of Neuroscience, with my mentor Paul Cisek.
In this review we describe how accumulation-to-bound models have been highly successful in explaining behavior in a very wide range of tasks. We also mention their limitations, which recently motivated several important modifications to their basic assumptions. The review especially discusses the duration of the sensory evidence integration and the stability of the decision threshold in natural situations.
Cisek P, Thura D (2022) Decision-making models over time. Oxford Research Encyclopedia of Neuroscience.
New accepted paper !
Happy to see this great collaborative work with Gerard Derosiere, Julie Duque and Paul Cisek accepted in PLOS Biology.
Derosiere G, Thura D, Cisek P, Duque J (2022) Hasty sensorimotor decisions rely on an overlap of broad and selective changes in motor activity. PLoS Biol. 20(4): e3001598.
Curious about the consequences of a decision or a movement error on the subsequent decision and motor performances in humans?
Happy to see my comment of the article: "Précis of Vigor: Neuroeconomics of Movement control" by Alaa A. Ahmed and Reza Shadmehr, published in Behavioral and Brain Sciences.
Happy to be part of another fruitful collaborative work with Gerard Derosiere, Julie Duque and Paul Cisek.
Happy to share a new article in press -"Trading accuracy for speed over the course of a decision", the result of a fruitful collaboration with Gerard Derosiere, Paul Cisek and Julie Duqué
Are motor costs part of the decision-making and movement initiation computations? Between time and effort, which motor cost is the most impactful for decision-making and movement initiation? How variable are effects of motor costs on behavior at the individual level?
Find some answers to these questions and more in our latest preprint. Congratulations Clara and Amelie on this nice behavioral study !
We are (virtually) here at
Please come by and say Hi to Amélie who will show you the effect of motor accuracy requirements on decision-making in both human and non-human primates.
Don't forget to come to Clara's poster which describes the effects of motor duration and energy costs on human decision-making and movement initiation.
Congrats Clara for presenting your first poster during an international meeting !
NCM 2021 was great ! Thank you to the organizers. We also thank all the attendees who came by and showed interest in our work.
Implantation planning in progress...
With the free software 3D Slicer, a CT-scan and a MRI scan done at the Cermep, we are now choosing the best location and orientation of the recording chamber so we can simultaneously record in PMd/M1, the putamen, GPe, GPi.
Happy to find out that my invited commentary on "Précis of Vigor: Neuroeconomics of Movement Control" by Reza Shadmehr and Alaa A. Ahmed, entitled "Neuroscience needs integrated behavior", has been officially accepted for publication in Behavioral and Brain Sciences. Stay tuned for the online version of the article.
April 20-22: Clara will present her poster on the effect of action duration and energy on decision-making during the 2021 annual meeting of the Society for Neural Control of Movement. - Online
New page on the site !
Learn more about the equipment we are using in the lab.
Very happy to find out that the team ATIP/Avenir label will be renewed and the research funded for two additional years (until August 2023).
Thank you to the Inserm and CNRS ATIP/Avenir committee for trusting my program.
Very grateful to Katja Heuer and Roberto Toro for making their beautiful poster free to download in high resolution. Aesthetic and educational decoration. Their paper on the evolution of neocortical folding across 34 primate species can be found here: 10.1016/j.cortex.2019.04.011
Very happy to see our latest paper discussed in the sensorimotor control and learning journal club. @Amelie_Reynaud showed how humans can flexibly adjust their decision and movement speed/accuracy trade-off depending on task constraints.
How do the cortex and the basal ganglia share labor during decision and action?
With Jean-Francois Cabana, Albert Feghaly and Paul Cisek we analyzed population activity from PMd, M1, dlPFC, GPe and GPi in two monkeys performing a decision task.
We show that decisions about actions involve a unified dynamical attractor system distributed across the cortex and basal ganglia.
Congratulations Clara Saleri for being awarded with a doctoral scholarship from the French Ministry of Research ! Very happy to welcome you onboard and I look forward to studying the neural bases of decision-making together !
Very happy to see the second paper of the lab accepted in one of my favorite journal, Journal of Neurophysiology ! Congratulations Amelie Reynaud and Clara Saleri on this important step toward a better understanding of the relationship between decision-making and motor control !
My Ph.D. research in Driss Boussaoud's lab focused on the FEF, a major component of the cerebral network that is thought to contribute to decision making, as well as to visual and oculomotor processes. We used single-neuron recordings in monkeys to test the hypothesis that FEF neurons integrate signals from the hand to ensure adapted ocular exploration of peripersonal space.
My post-doctoral position in Paul Cisek’s lab provided me with the opportunity to pursue the exploration of complex integrative functions, i.e. decision making, in brain regions such as PMd, M1 and PFC. We investigated the neural correlates of dynamic decision-making in monkeys trained to perform a reach decision task. We showed that premotor and primary motor cortex activity reflects the competition between potential options and signals the commitment to a choice before movement initiation.
As a research associate in Paul Cisek's lab at University of Montreal, we explored the behavior and the neural bases of speed-accuracy trade-off adjustments during dynamic decisions and movement execution. We investigate this question under the affordance competition and the urgency-gating frameworks.
On this page I describe the different pieces of equipment that we are currently using in the lab, for both behavioral and electrophysiological experiments conducted in humans and monkeys
In this section I share articles that caught my eye and I make some material available, mostly slides from various courses or talks. Feel free to check it out