Lyon Neuroscience Research Center
Lyon Neuroscience Research Center - ImpAct Team
Inserm U1028 - CNRS UMR 5292
16 avenue Doyen Lépine
69676 Bron Cedex
Phone: +33 (0)4 72 91 34 14
E-mail : email@example.com
Urgent decision-making between actions
Cortico-basal ganglia network
NEWS (last update: Feb 02, 2020)
Please check out the latest paper published in the Journal of Neurophysiology describing an ICMS experiment performed in Montreal with Paul Cisek. We show that stimulation of monkey PMd and, to lesser extend, M1 delays the commitment to an action choice:
My paper describing the effects of decision urgency on movement kimematics in humans has been discussed during the journal club of Paul Cisek's group at University of Montreal. Such a satisfactory feeling...
The first paper of the lab is out ! The study shows that decision urgency strongly influences movement speed and duration in humans, irrespective of practice load. Please check it out:
New material available: slides from two courses given at University Claude Bernard Lyon 1 - Check it out !
If you are in Chicago for SfN 2019 and you are interested in decision-making, motor control, cortico-basal ganglia network, neurophysiology and modeling? Come see Paul Cisek presenting our poster on Tuesday afternoon (606.13 - BB19)
Our latest paper is a collaborative work with Gerard Derosiere and Julie Duque suggesting that human M1 cortex is weakly involved in deciding between action choices. Please check it out:
Please check out this interesting study, hot off the press, in which we show that a primary reinforcer, thirst, modulates human subjects kinematics during reaching and grasping a glass.
Patrice Revol, Sarah Collette, Zoe Boulot, Alexandre Foncelle, Chiharu Niki, David Thura, Akila Imai, Sophie Jacquin-Courtois, Michel Cabanac, François Osiurak and Yves Rossetti
Very happy to promote our latest article in The Neuroscientist, a review paper in which we (with Matt Carland and Paul Cisek) argue that an urgency-based mechanism provides a potential link between personality traits (e.g. impulsivity) and some clinical disorders (e.g. Parkinson’s disease).
Very pleased to contribute to the upcoming workshop on Cognitive Control and Performance Monitoring - In memory of Laurence Questienne
I will be giving a talk entitled:
June 14, 2019 - 17.50 pm
Please check the full program
Selection and invigoration of behavior: a role for the cortico-basal ganglia network
Friday, April 05, 2019, 12pm
Inserm - Ecole Normale Supérieure
29, rue d’Ulm, 75005 Paris
Insightful 2-retreat for the new Auvergne-Rhône-Alpes Inserm researchers in the beautiful domain Les Pensieres
The human experimental setup is ready, first subjects are expected on February. Next setup phase: the monkey experimental environment... In the meantime, check out the tentative logo of the lab:
As part of the UCBL Master II Neuroscience program, I will be giving a talk entitled :
Electrophysiological approaches to decision-making
on Tuesday 13th November, 2018
Salle 203, Bâtiment Jean-François Cier (Campus Lyon Santé Est)
Interested in the neuroscience of decision between actions? Come work with me in Lyon !
2-years funded postdoctoral position available, starting fall 2019.
Here is Paul and I latest piece, a review on the neural circuits for action selection:
In a chapter, we summarize our recent work on the role of the PMd/M1-BG circuit during decision between actions, we propose a way to map neural circuits and decision types and we finally speculate on the respective functions of cortex and BG during goal oriented behavior.
Proud and delighted to announce that on September 2018 I'll be starting my own research program as a tenured INSERM researcher in the Lyon Neuroscience Research Center, Bron (France)
Delighted to contribute to the upcoming workshop on Probabilities and Optimal Inference to Understand the Brain:
I will be giving a talk entitled:
Brain circuits of urgent decisions
April 6, 2018 - 10.30 am
Please check this tentative summary out !
(and the cool picture)
Régulation du compromis vitesse-précision pendant la prise de décision et l’exécution motrice : théorie, comportement et bases neuronales*
Jeudi, 18 Janvier, 2018 à 10:30
Université du Québec à Montréal
Salle PK-5115, Pavillon Président-Kennedy (PK)
201, avenue du Président-Kennedy, H2X 3Y7
* Will be delivered in French
My ATIP-Avenir grant
has been awarded !!
More about my first independent research program soon
Shopping and recruitment (post-doc) to come very soon too !
!!! New paper out !!!
by David Thura and Paul Cisek
95 (5) : 1160 - 1170, 2017
Please also check out this preview by Dr. Emilio Salinas
and the Highlight published in Nature Reviews Neuroscience by Dr. Katherine Walley
My Ph.D. research focused on the FEF, a major component of the cerebral network that is thought to contribute to decision making, as well as to visual and oculomotor processes. We used single-neuron recordings in monkeys to test the hypothesis that FEF neurons integrate signals from the hand to ensure adapted ocular exploration of peripersonal space.
My post-doctoral position in Paul Cisek’s lab provided me with the opportunity to pursue the exploration of complex integrative functions, i.e. decision making, in brain regions such as PMd, M1 and PFC. We investigated the neural correlates of dynamic decision-making in monkeys trained to perform a reach decision task. We showed that premotor and primary motor cortex activity reflects the competition between potential options and signals the commitment to a choice before movement initiation.
As a research associate in Paul Cisek's lab at University of Montreal, we explored the behavior and the neural bases of speed-accuracy trade-off adjustments during dynamic decisions and movement execution. We investigate this question under the affordance competition and the urgency-gating frameworks.
Please click here for a more detailed overview of my career and accomplishments
In this section I make some material available, mostly slides from various courses or talks. Feel free to check it out